Beschreibung:
<jats:title>How ribosomes are made</jats:title>
<jats:p>
The formation of eukaryotic ribosomes is a complex process that starts with transcription of a large precursor RNA that assembles into a large 90S preribosome, which matures to finally give the 40S small subunit of the ribosome. Cheng
<jats:italic>et al.</jats:italic>
and Du
<jats:italic>et al.</jats:italic>
give insight into this process, using cryo–electron microscopy to look at intermediates along the pathway. Together, these studies reveal how a cast of molecular players act to coordinate the compositional and structural changes that transform the 90S preribosome into a pre-40S subunit.
</jats:p>
<jats:p>
<jats:italic>Science</jats:italic>
, this issue p.
<jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6510" page="1470" related-article-type="in-this-issue" vol="369" xlink:href="10.1126/science.abb4119">1470</jats:related-article>
, p.
<jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6510" page="1477" related-article-type="in-this-issue" vol="369" xlink:href="10.1126/science.aba9690">1477</jats:related-article>
</jats:p>