• Medientyp: E-Artikel
  • Titel: Characterization of a Daptomycin-Nonsusceptible Vancomycin-Intermediate Staphylococcus aureus Strain in a Patient with Endocarditis
  • Beteiligte: Julian, Kathleen; Kosowska-Shick, Klaudia; Whitener, Cynthia; Roos, Martin; Labischinski, Harald; Rubio, Aileen; Parent, Leslie; Ednie, Lois; Koeth, Laura; Bogdanovich, Tatiana; Appelbaum, Peter C.
  • Erschienen: American Society for Microbiology, 2007
  • Erschienen in: Antimicrobial Agents and Chemotherapy
  • Sprache: Englisch
  • DOI: 10.1128/aac.00559-07
  • ISSN: 0066-4804; 1098-6596
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  • Beschreibung: <jats:title>ABSTRACT</jats:title> <jats:p> We analyzed the emergence of daptomycin nonsusceptibility in a patient with persistent vancomycin-intermediate <jats:italic>Staphylococcus aureus</jats:italic> (VISA) bacteremia. The daptomycin-nonsusceptible VISA's cell wall demonstrated a reduction in muramic acid <jats:italic>O</jats:italic> -acetylation, a phenotypic parameter not previously reported for VISA; some isolates also contained a single point mutation in the <jats:italic>mprF</jats:italic> gene. </jats:p>
  • Zugangsstatus: Freier Zugang