Erschienen:
American Society for Microbiology, 2007
Erschienen in:Antimicrobial Agents and Chemotherapy
Sprache:
Englisch
DOI:
10.1128/aac.00559-07
ISSN:
0066-4804;
1098-6596
Entstehung:
Anmerkungen:
Beschreibung:
<jats:title>ABSTRACT</jats:title>
<jats:p>
We analyzed the emergence of daptomycin nonsusceptibility in a patient with persistent vancomycin-intermediate
<jats:italic>Staphylococcus aureus</jats:italic>
(VISA) bacteremia. The daptomycin-nonsusceptible VISA's cell wall demonstrated a reduction in muramic acid
<jats:italic>O</jats:italic>
-acetylation, a phenotypic parameter not previously reported for VISA; some isolates also contained a single point mutation in the
<jats:italic>mprF</jats:italic>
gene.
</jats:p>