Erschienen:
American Society for Microbiology, 2019
Erschienen in:
Antimicrobial Agents and Chemotherapy, 63 (2019) 10
Sprache:
Englisch
DOI:
10.1128/aac.00800-19
ISSN:
0066-4804;
1098-6596
Entstehung:
Anmerkungen:
Beschreibung:
Sitafloxacin showed potent activity against various respiratory pathogens. Blood and bronchoalveolar lavage (BAL) fluid samples were obtained from 12 subjects after a single oral dose of sitafloxacin 200 mg. The mean ± SD (median) maximum ratio of epithelial lining fluid (ELF) to unbound plasma concentration was 1.02 ± 0.58 (1.33).