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Fehling, Helena; Choy, Siew Ling; Ting, Frederic; Landschulze, Dirk; Bernin, Hannah; Lender, Sarah Corinna; Mühlenpfordt, Melina; Bifeld, Eugenia; Eick, Julia; Marggraff, Claudia; Kottmayr, Nadine; Groneberg, Marie; Hoenow, Stefan; Sellau, Julie; Clos, Joachim; Meier, Chris; Lotter, Hannelore

Antileishmanial Effects of Synthetic Eh PIb Analogs Derived from the Entamoeba histolytica Lipopeptidephosphoglycan

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  • Medientyp: E-Artikel
  • Titel: Antileishmanial Effects of Synthetic Eh PIb Analogs Derived from the Entamoeba histolytica Lipopeptidephosphoglycan
  • Beteiligte: Fehling, Helena; Choy, Siew Ling; Ting, Frederic; Landschulze, Dirk; Bernin, Hannah; Lender, Sarah Corinna; Mühlenpfordt, Melina; Bifeld, Eugenia; Eick, Julia; Marggraff, Claudia; Kottmayr, Nadine; Groneberg, Marie; Hoenow, Stefan; Sellau, Julie; Clos, Joachim; Meier, Chris; Lotter, Hannelore
  • Erschienen: American Society for Microbiology, 2020
  • Erschienen in: Antimicrobial Agents and Chemotherapy
  • Sprache: Englisch
  • DOI: 10.1128/aac.00161-20
  • ISSN: 0066-4804; 1098-6596
  • Schlagwörter: Infectious Diseases ; Pharmacology (medical) ; Pharmacology
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p> With an estimated number of new cases annually of approximately 1.4 million, leishmaniasis belongs to the most important parasitic diseases in the world. Nevertheless, existing drugs against leishmaniasis in general have several drawbacks that urgently necessitate new drug development. A glycolipid molecule of the intestinal protozoan parasite <jats:named-content content-type="genus-species">Entamoeba histolytica</jats:named-content> and its synthetic analogs previously showed considerable immunotherapeutic effects against <jats:named-content content-type="genus-species">Leishmania major</jats:named-content> infection. </jats:p>
  • Zugangsstatus: Freier Zugang