Hawser, Stephen P.;
Bouchillon, Samuel K.;
Hoban, Daryl J.;
Badal, Robert E.;
Cantón, Rafael;
Baquero, Fernando
Incidence and Antimicrobial Susceptibility of Escherichia coli and Klebsiella pneumoniae with Extended-Spectrum β-Lactamases in Community- and Hospital-Associated Intra-Abdominal Infections in Europe: Results of the 2008 Study for Monitoring Antimicrobial Resistance Trends (SMART)
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Medientyp:
E-Artikel
Titel:
Incidence and Antimicrobial Susceptibility of Escherichia coli and Klebsiella pneumoniae with Extended-Spectrum β-Lactamases in Community- and Hospital-Associated Intra-Abdominal Infections in Europe: Results of the 2008 Study for Monitoring Antimicrobial Resistance Trends (SMART)
Beteiligte:
Hawser, Stephen P.;
Bouchillon, Samuel K.;
Hoban, Daryl J.;
Badal, Robert E.;
Cantón, Rafael;
Baquero, Fernando
Erschienen:
American Society for Microbiology, 2010
Erschienen in:Antimicrobial Agents and Chemotherapy
Beschreibung:
<jats:title>ABSTRACT</jats:title>
<jats:p>
From 2002 to 2008, there was a significant increase in extended-spectrum beta-lactamase (ESBL)-positive
<jats:italic>Escherichia coli</jats:italic>
isolates in European intra-abdominal infections, from 4.3% in 2002 to 11.8% in 2008 (
<jats:italic>P</jats:italic>
< 0.001), but not for ESBL-positive
<jats:italic>Klebsiella pneumoniae</jats:italic>
isolates (16.4% to 17.9% [
<jats:italic>P</jats:italic>
> 0.05]). Hospital-associated isolates were more common than community-associated isolates, at 14.0% versus 6.5%, respectively, for
<jats:italic>E. coli</jats:italic>
(
<jats:italic>P</jats:italic>
< 0.001) and 20.9% versus 5.3%, respectively, for
<jats:italic>K. pneumoniae</jats:italic>
(
<jats:italic>P</jats:italic>
< 0.01). Carbapenems were consistently the most active drugs tested.
</jats:p>