• Medientyp: E-Artikel
  • Titel: Prominent Binding of Human and Equine Fibrinogen to Streptococcus equi subsp. zooepidemicus Is Mediated by Specific SzM Types and Is a Distinct Phenotype of Zoonotic Isolates
  • Beteiligte: Bergmann, René; Jentsch, Maria-Christin; Uhlig, Albrecht; Müller, Uwe; van der Linden, Mark; Rasmussen, Magnus; Waller, Andrew; von Köckritz-Blickwede, Maren; Baums, Christoph Georg
  • Erschienen: American Society for Microbiology, 2019
  • Erschienen in: Infection and Immunity
  • Sprache: Englisch
  • DOI: 10.1128/iai.00559-19
  • ISSN: 0019-9567; 1098-5522
  • Schlagwörter: Infectious Diseases ; Immunology ; Microbiology ; Parasitology
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  • Beschreibung: <jats:p> <jats:named-content content-type="genus-species">Streptococcus equi</jats:named-content> subsp. <jats:italic>zooepidemicus</jats:italic> is an important pathogen in horses that causes severe diseases such as pneumonia and abortion. Furthermore, it is a zoonotic agent, and contact with horses is a known risk factor. In this study, we investigated the working hypothesis that the zoonotic potential varies among <jats:named-content content-type="genus-species">S. equi</jats:named-content> subsp. <jats:italic>zooepidemicus</jats:italic> strains in association with differences in M-like protein-mediated binding of host plasma proteins. </jats:p>
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