Erschienen:
American Society for Microbiology, 2019
Erschienen in:
Infection and Immunity, 87 (2019) 11
Sprache:
Englisch
DOI:
10.1128/iai.00329-19
ISSN:
0019-9567;
1098-5522
Entstehung:
Anmerkungen:
Beschreibung:
Neutrophils contribute to lung injury in acute pneumococcal pneumonia. The interleukin 17 receptor E (IL-17RE) is the functional receptor for the epithelial-derived cytokine IL-17C, which is known to mediate innate immune functions. The aim of this study was to investigate the contribution of IL-17RE/IL-17C to pulmonary inflammation in a mouse model of acute Streptococcus pneumoniae pneumonia.