• Medientyp: E-Artikel
  • Titel: Utilization of Palmitic Acid by Mycobacterium avium
  • Beteiligte: McCarthy, Charlotte
  • Erschienen: American Society for Microbiology, 1971
  • Erschienen in: Infection and Immunity, 4 (1971) 3, Seite 199-204
  • Sprache: Englisch
  • DOI: 10.1128/iai.4.3.199-204.1971
  • ISSN: 0019-9567; 1098-5522
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  • Beschreibung: Mycobacterium avium accumulates 14 C-palmitic acid with saturation kinetics; the process is both temperature dependent and p H sensitive. The fatty acid is incorporated into triglyceride in vivo and the conversion is detectable within 5 min after exposure of the cells to 14 C-palmitic acid. The triglyceride is rapidly utilized because 14 CO 2 evolution from it begins within 30 min after 14 C-palmitic acid accumulation. Data from silicic acid column chromatography of extracts of cultures that have divided many times in medium containing 14 C-palmitic acid indicate that a large proportion of the cell lipid is triglyceride, but the radioactivity is widely dispersed among the other lipids. It is estimated that about 5% of the cell dry weight is triglyceride in a postexponential culture.
  • Zugangsstatus: Freier Zugang