Beschreibung:
<jats:title>ABSTRACT</jats:title>
<jats:p>
Biofilm cultures of
<jats:named-content content-type="genus-species">Burkholderia cepacia</jats:named-content>
complex (BCC) infection have been found to generate the nonvolatile cyanide ion. We investigated if gaseous hydrogen cyanide (HCN) was a marker of BCC infection. Selected ion flow tube mass spectrometry analysis showed HCN was not elevated in the headspace of planktonic or biofilm cultures or in the exhaled breath of adult cystic fibrosis patients with chronic BCC infection. HCN is therefore not an
<jats:italic>in vitro</jats:italic>
or
<jats:italic>in vivo</jats:italic>
marker of BCC.
</jats:p>