• Medientyp: E-Artikel
  • Titel: Production of BRO β-Lactamases and Resistance to Complement in European Moraxella catarrhalis Isolates
  • Beteiligte: Schmitz, Franz-Josef; Beeck, Andreas; Perdikouli, Mirella; Boos, Mechthild; Mayer, Susanne; Scheuring, Sybille; Köhrer, Karl; Verhoef, Jan; Fluit, Ad C.
  • Erschienen: American Society for Microbiology, 2002
  • Erschienen in: Journal of Clinical Microbiology
  • Sprache: Englisch
  • DOI: 10.1128/jcm.40.4.1546-1548.2002
  • ISSN: 0095-1137; 1098-660X
  • Schlagwörter: Microbiology (medical)
  • Entstehung:
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  • Beschreibung: <jats:title>ABSTRACT</jats:title> <jats:p> Of the 419 <jats:italic>Moraxella catarrhalis</jats:italic> isolates collected during the 1997-1999 European SENTRY surveillance study, 385 (92%) were β-lactamase positive. Twenty-two (5.7%) produced BRO-2 β-lactamase. Twenty-one new mutations were found in the putative promoter region of the <jats:italic>bro</jats:italic> genes. Nineteen percent of all isolates tested were complement sensitive. Resistance to β-lactams is not linked to the phylogenetic lineages associated with susceptibility to complement. </jats:p>
  • Zugangsstatus: Freier Zugang