Beschreibung:
<jats:p>
<jats:sc>Firshein, William</jats:sc>
(Wesleyan University, Middletown, Conn.),
<jats:sc>and Bernadette A. Gargan</jats:sc>
. Influence of deoxyribonucleic acid degradation products and orthophosphate on uptake of deoxynucleosides in pneumococcus type III. J. Bacteriol.
<jats:bold>90:</jats:bold>
337–342. 1965.—The uptake of specific C
<jats:sup>14</jats:sup>
-deoxynucleosides by a type III encapsulated (virulent) strain of pneumococcus in resting-cell suspensions is enhanced when such deoxynucleosides are added as part of a supplement consisting of other deoxynucleosides, deoxynucleotides, an oligo(deoxy)nucleotide fraction derived from a deoxyribonuclease-treated calf-thymus deoxyribonucleic acid, and orthophosphate. Ribonucleic acid degradation products or yeast extract are ineffective in this respect. Mixtures of deoxynucleosides and deoxynucleotides stimulate uptake of a specific deoxynucleoside during early stages of incubation, whereas orthophosphate and, to a limited extent, the oligonucleotides stimulate uptake during later stages of incubation. The stimulated uptake of specific deoxynucleosides can be abolished by adding chloramphenicol.
</jats:p>