• Medientyp: E-Artikel
  • Titel: Improved Bacterial Single-Cell RNA-Seq through Automated MATQ-Seq and Cas9-Based Removal of rRNA Reads
  • Beteiligte: Homberger, Christina; Hayward, Regan J.; Barquist, Lars; Vogel, Jörg
  • Erschienen: American Society for Microbiology, 2023
  • Erschienen in: mBio
  • Sprache: Englisch
  • DOI: 10.1128/mbio.03557-22
  • ISSN: 2150-7511
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p>Gene expression heterogeneity among isogenic bacteria is linked to clinically relevant scenarios, like biofilm formation and antibiotic tolerance. The recent development of bacterial single-cell RNA sequencing (scRNA-seq) enables the study of cell-to-cell variability in bacterial populations and the mechanisms underlying these phenomena.</jats:p>
  • Zugangsstatus: Freier Zugang