Development and Validation of a Sensitive and Robust Multiplex Antigen Capture Assay to Quantify Streptococcus pneumoniae Serotype-Specific Capsular Polysaccharides in Urine

Medientyp: E-Artikel
Titel: Development and Validation of a Sensitive and Robust Multiplex Antigen Capture Assay to Quantify Streptococcus pneumoniae Serotype-Specific Capsular Polysaccharides in Urine
Beteiligte: Rajam, Gowrisankar; Zhang, Yuhua; Antonello, Joseph M.; Grant-Klein, Rebecca J.; Cook, Lauren; Panemangalore, Reshma; Pham, Huy; Cooper, Stephanie; Steinmetz, Thomas D.; Nguyen, Jennifer; Pletz, Mathias W.; Barten-Neiner, Grit; Murphy, Rocio D.; Rubinstein, Leonard J.; Nolan, Katrina M.
Erschienen: American Society for Microbiology, 2022
Erschienen in: mSphere, 7 (2022) 4
Sprache: Englisch
DOI: 10.1128/msphere.00114-22
ISSN: 2379-5042
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Beschreibung: <jats:p> <jats:named-content content-type="genus-species">Streptococcus pneumoniae</jats:named-content> has more than 90 serotypes capable of causing a range of disease manifestations, including otitis media, pneumonia, and invasive diseases, such as bacteremia or meningitis. Only a minority (<10%) of pneumococcal diseases are bacteremic with known serotype distribution. </jats:p>
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