Sie können Bookmarks mittels Listen verwalten, loggen Sie sich dafür bitte in Ihr SLUB Benutzerkonto ein.
Medientyp:
E-Artikel
Titel:
Toxoplasma gondiiseroprevalence in the Portuguese population: comparison of three cross-sectional studies spanning three decades
Beteiligte:
Gargaté, Maria João;
Ferreira, Idalina;
Vilares, Anabela;
Martins, Susana;
Cardoso, Carlos;
Silva, Susana;
Nunes, Baltazar;
Gomes, João Paulo
Erschienen:
BMJ, 2016
Erschienen in:
BMJ Open, 6 (2016) 10, Seite e011648
Sprache:
Englisch
DOI:
10.1136/bmjopen-2016-011648
ISSN:
2044-6055
Entstehung:
Anmerkungen:
Beschreibung:
BackgroundToxoplasma gondiiis an obligate intracellular protozoan infecting up to one-third of the world's population, constituting a life threat if transmitted from mother to child during pregnancy. In Portugal, there is a lack of knowledge of the current epidemiological situation, as the unique toxoplasmosis National Serological Survey was performed in 1979/1980.MethodsWe studied the seroprevalence trends in the Portuguese general population over the past 3 decades, by assessing chronological spread cross-sectional studies, with special focus on women of childbearing age, by age group, region and gender.ResultsTheT. gondiioverall seroprevalence decreased from 47% in 1979/1980 to 22% (95% CI 20% to 24%) in 2013. Generally, we observed that the prevalence ofT. gondiiIgG increased significantly with age and it decreased over time, both in the general population and in the childbearing women (18% prevalence in 2013).ConclusionsThe scenario observed for the latter indicates that more than 80% of childbearing women are susceptible to primary infection yielding a risk of congenital toxoplasmosis and respective sequelae. Since there is no vaccine to prevent human toxoplasmosis, the improvement of primary prevention constitutes a major tool to avoid infection in such susceptible groups.