• Medientyp: E-Artikel
  • Titel: Scanning and transmission electron microscopic aspects of the nasal acilia syndrome
  • Beteiligte: Dudley, James P.; Welch, Michael J.; Carney, Jean M.; Stiehm, E. Richard; Soderberg‐Warner, Margaret
  • Erschienen: Wiley, 1982
  • Erschienen in: The Laryngoscope
  • Sprache: Englisch
  • DOI: 10.1288/00005537-198203000-00014
  • ISSN: 0023-852X; 1531-4995
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  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>A 3‐month‐old boy was admitted with failure to thrive and persistent fevers. During a 4 month hospitalization for treatment of suspected sepsis, persistent purulent nasal discharge developed. Biopsies of his nasal mucosa on 3 separate occasions disclosed thinned respiratory epithelium and a complete absence of cilia when examined by electron microscopy (EM). Despite an initial granulocytopenia and a wide range in T‐cell numbers, he did not show any evidence of lower respiratory tract infection. A tracheal biopsy processed for EM demonstrated normal ciliated epithelium. This patient appears to have an unrecognized syndrome of normal tracheal cilia but absent nasal cilia.</jats:p>