Sie können Bookmarks mittels Listen verwalten, loggen Sie sich dafür bitte in Ihr SLUB Benutzerkonto ein.
Medientyp:
E-Artikel
Titel:
Hyperbolic dispersion metasurfaces for molecular biosensing
Beteiligte:
Palermo, Giovanna;
Sreekanth, Kandammathe Valiyaveedu;
Maccaferri, Nicolò;
Lio, Giuseppe Emanuele;
Nicoletta, Giuseppe;
De Angelis, Francesco;
Hinczewski, Michael;
Strangi, Giuseppe
Erschienen:
Walter de Gruyter GmbH, 2020
Erschienen in:Nanophotonics
Sprache:
Nicht zu entscheiden
DOI:
10.1515/nanoph-2020-0466
ISSN:
2192-8614;
2192-8606
Entstehung:
Anmerkungen:
Beschreibung:
<jats:title>Abstract</jats:title><jats:p>Sensor technology has become increasingly crucial in medical research and clinical diagnostics to directly detect small numbers of low-molecular-weight biomolecules relevant for lethal diseases. In recent years, various technologies have been developed, a number of them becoming core label-free technologies for detection of cancer biomarkers and viruses. However, to radically improve early disease diagnostics, tracking of disease progression and evaluation of treatments, today’s biosensing techniques still require a radical innovation to deliver high sensitivity, specificity, diffusion-limited transport, and accuracy for both nucleic acids and proteins. In this review, we discuss both scientific and technological aspects of hyperbolic dispersion metasurfaces for molecular biosensing. Optical metasurfaces have offered the tantalizing opportunity to engineer wavefronts while its intrinsic nanoscale patterns promote tremendous molecular interactions and selective binding. Hyperbolic dispersion metasurfaces support high-<jats:italic>k</jats:italic>modes that proved to be extremely sensitive to minute concentrations of ultralow-molecular-weight proteins and nucleic acids.</jats:p>