• Medientyp: E-Artikel
  • Titel: Hypothetical Proteins as Predecessors of Long Non-coding RNAs
  • Beteiligte: Malik, Girik; Agarwal, Tanu; Raj, Utkarsh; Sundararajan, Vijayaraghava Seshadri; Bandapalli, Obul Reddy; Suravajhala, Prashanth
  • Erschienen: Bentham Science Publishers Ltd., 2020
  • Erschienen in: Current Genomics
  • Sprache: Englisch
  • DOI: 10.2174/1389202921999200611155418
  • ISSN: 1389-2029
  • Schlagwörter: Genetics (clinical) ; Genetics
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:sec> <jats:title /> <jats:p>Hypothetical Proteins [HP] are the transcripts predicted to be expressed in an organism, but no evidence of it exists in gene banks. On the other hand, long non-coding RNAs [lncRNAs] are the transcripts that might be present in the 5’ UTR or intergenic regions of the genes whose lengths are above 200 bases. With the known unknown [KU] regions in the genomes rapidly existing in gene banks, there is a need to understand the role of open reading frames in the context of annotation. In this commentary, we emphasize that HPs could indeed be the predecessors of lncRNAs.</jats:p> </jats:sec>
  • Zugangsstatus: Freier Zugang