Treatment and outcomes for early non-small-cell lung cancer: a retrospective analysis of a Portuguese hospital database

Medientyp: E-Artikel

Titel: Treatment and outcomes for early non-small-cell lung cancer: a retrospective analysis of a Portuguese hospital database

Beteiligte: Soares, Marta; Antunes, Luís; Redondo, Patrícia; Borges, Marina; Hermans, Ruben; Patel, Dony; Grimson, Fiona; Munro, Robin; Chaib, Carlos; Lacoin, Laure; Daumont, Melinda; Penrod, John R; O'Donnell, John C; Bento, Maria José; Gonçalves, Francisco Rocha

Erschienen: Future Medicine Ltd, 2021

Sprache: Englisch

DOI: 10.2217/lmt-2020-0028

ISSN: 1758-1974; 1758-1966

Schlagwörter: Pulmonary and Respiratory Medicine ; Oncology

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Beschreibung: Aim: This observational study evaluated treatment patterns and survival for patients with stage I–IIIA non-small-cell lung cancer (NSCLC). Materials & methods: Adults newly diagnosed with NSCLC in 2012–2016 at IPO-Porto hospital were included. Treatment data were available for patients diagnosed in 2015–2016. Results: 495 patients were included (median age: 67 years). The most common treatments were surgery alone or with another therapy (stage I: 66%) and systemic anticancer therapy plus radiotherapy (stage II: 54%; stage IIIA: 59%). One-year OS (95% CI) for patients with stage I, II and IIIA NSCLC (diagnosed 2012–2016) were 92% (88–96), 71% (62–82) and 69% (63–75), respectively; one-year OS (95% CI) for treated patients with stage I–II or stage IIIA NSCLC (diagnosed 2015–2016) were 89% (81–97) and 86% (75–98) for non-squamous cell and 76% (60–95) and 49% (34–70) for squamous cell NSCLC. Conclusion: Treatment advances are strongly needed for stage I–IIIA NSCLC, especially for patients with squamous cell histology.

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