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YI YUAN, CHENG; KONG, YEE W.; AMOORE, TESS; BROWN, KATRIN; GROSMAN, BENYAMIN; JENKINS, ALICIA; JONES, HANNAH; KURTZ, NATALIE; LEE, MELISSA H.; MACISAAC, RICHARD; NETZER, EMMA; PALDUS, BARBORA; ROBINSON, LESLEY; ROY, ANIRBAN; SIMS, CATRIONA M.; TRAWLEY, STEVEN; VOGRIN, SARA; O'NEAL, DAVID N.

922-P: Improved Satisfaction while Maintaining Safety and High Time in Range (TIR) with a Medtronic Investigational Enhanced Advanced Hybrid Closed-Loop System (eAHCL)

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  • Medientyp: E-Artikel
  • Titel: 922-P: Improved Satisfaction while Maintaining Safety and High Time in Range (TIR) with a Medtronic Investigational Enhanced Advanced Hybrid Closed-Loop System (eAHCL)
  • Beteiligte: YI YUAN, CHENG; KONG, YEE W.; AMOORE, TESS; BROWN, KATRIN; GROSMAN, BENYAMIN; JENKINS, ALICIA; JONES, HANNAH; KURTZ, NATALIE; LEE, MELISSA H.; MACISAAC, RICHARD; NETZER, EMMA; PALDUS, BARBORA; ROBINSON, LESLEY; ROY, ANIRBAN; SIMS, CATRIONA M.; TRAWLEY, STEVEN; VOGRIN, SARA; O'NEAL, DAVID N.
  • Erschienen: American Diabetes Association, 2023
  • Erschienen in: Diabetes
  • Sprache: Englisch
  • DOI: 10.2337/db23-922-p
  • ISSN: 0012-1797
  • Schlagwörter: Endocrinology, Diabetes and Metabolism ; Internal Medicine
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p>Background: Hybrid closed loop (HCL) systems are evolving. We aimed to assess treatment satisfaction and glucose control with an investigational eAHCL system.</jats:p> <jats:p>Methods: Adults with type 1 diabetes (T1D) received sequentially the MiniMed™ 780G /Guardian™ Sensor 3 AHCL system, and a Medtronic investigational eAHCL system each for 12 weeks. The eAHCL system incorporates updated software, a new simple to use, no calibration, all-in-one sensor, and 7 day extended wear infusion set. The primary outcome was difference in treatment satisfaction measured using “current” and “change” versions of the Diabetes Technology Questionnaire (DTQ) following each 12 week period. Secondary outcomes included time spent changing infusion sets and sensors recorded on a phone app and CGM metrics.</jats:p> <jats:p>Results: Twenty-one adults (11 men, mean [SD] age 48 [12.4] years) completed the trial. DTQ “current” score improved on eAHCL, and 86% of participants reported less “Effort to keep low blood sugar from happening” on DTQ “change”. There was less fear of hypoglycemia; more time in Auto Mode; fewer alarms; less time spent changing infusion sets and sensors; reduced CGM hypoglycemia and glycemic variability (Table 1).</jats:p> <jats:p>Conclusions: Transition to eAHCL in T1D adults resulted in a better user experience and reduced fear of and time in hypoglycemia while maintaining safety and &amp;gt;80% TIR.</jats:p> <jats:p /> <jats:sec> <jats:title>Disclosure</jats:title> <jats:p>C.Yuan: None. R.Macisaac: None. E.Netzer: None. B.Paldus: None. L.Robinson: None. A.Roy: Employee; Medtronic. C.M.Sims: Stock/Shareholder; Medtronic. S.Trawley: Research Support; Insulet Corporation, Juvenile Diabetes Research Foundation (JDRF). S.Vogrin: None. D.N.O'neal: None. Y.W.Kong: None. T.Amoore: None. K.Brown: None. B.Grosman: Employee; Medtronic. A.Jenkins: Advisory Panel; Insulet Corporation, Board Member; Insulin for Life, Research Support; Abbott Diabetes, Medtronic, Hemsley Charitable Trust, Juvenile Diabetes Research Foundation (JDRF), National Institutes of Health. H.Jones: None. N.Kurtz: Employee; Medtronic. M.H.Lee: Speaker's Bureau; Medtronic.</jats:p> </jats:sec>
  • Zugangsstatus: Freier Zugang