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de Freitas Paganoti, Cristiane; Alkmin da Costa, Rafaela; Papageorghiou, Aris T.; da Silva Costa, Fabrício; Quintana, Silvana Maria; Graziela de Godoi, Luciana; Adriana Jiménez Monroy, Nátaly; Sacramento Rodrigues, Agatha; Pulcineli Vieira Francisco, Rossana

COVID-19 Vaccines Confer Protection in Hospitalized Pregnant and Postpartum Women with Severe COVID-19: A Retrospective Cohort Study

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  • Medientyp: E-Artikel
  • Titel: COVID-19 Vaccines Confer Protection in Hospitalized Pregnant and Postpartum Women with Severe COVID-19: A Retrospective Cohort Study
  • Beteiligte: de Freitas Paganoti, Cristiane; Alkmin da Costa, Rafaela; Papageorghiou, Aris T.; da Silva Costa, Fabrício; Quintana, Silvana Maria; Graziela de Godoi, Luciana; Adriana Jiménez Monroy, Nátaly; Sacramento Rodrigues, Agatha; Pulcineli Vieira Francisco, Rossana
  • Erschienen: MDPI AG, 2022
  • Erschienen in: Vaccines, 10 (2022) 5, Seite 749
  • Sprache: Englisch
  • DOI: 10.3390/vaccines10050749
  • ISSN: 2076-393X
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p>The coronavirus disease 2019 (COVID-19) pandemic has had deleterious effects among the obstetric population. Pregnant and postpartum women constitute a high-risk group for severe COVID-19. Vaccination reduces the risk of infection, but it is not known whether women who become infected despite vaccination have a milder course of disease than those who had not been vaccinated. This retrospective cohort study evaluated whether vaccination reduces the severity of COVID-19 infection, as measured by severe maternal morbidity and mortality among hospitalized pregnant and postpartum individuals. A total of 2284 pregnant and postpartum women hospitalized with severe COVID-19 were included. Those who did and who did not receive COVID-19 vaccination were compared. The rates of intensive care unit admission, intubation, and mortality were significantly lower among subjects in the vaccinated group (p &lt; 0.001, p &lt; 0.001 and p &lt; 0.001, respectively). The numbers of patients who needed to be vaccinated to avoid one case of intensive care unit admission, intubation, or death due to COVID-19 were 7, 7, and 9, respectively. The COVID-19 vaccine offers protective effects against intensive care unit admission, intubation, and death in hospitalized pregnant and postpartum women with severe SARS-CoV-2-induced SARS.</jats:p>
  • Zugangsstatus: Freier Zugang