• Medientyp: E-Artikel
  • Titel: Beyond Sentinel Lymph Node: Outcomes of Indocyanine Green-Guided Pelvic Lymphadenectomy in Endometrial and Cervical Cancer
  • Beteiligte: Chiofalo, Benito; Laganà, Antonio Simone; Ghezzi, Fabio; Certelli, Camilla; Casarin, Jvan; Bruno, Valentina; Sperduti, Isabella; Chiantera, Vito; Peitsidis, Panagiotis; Vizza, Enrico
  • Erschienen: MDPI AG, 2023
  • Erschienen in: International Journal of Environmental Research and Public Health, 20 (2023) 4, Seite 3476
  • Sprache: Englisch
  • DOI: 10.3390/ijerph20043476
  • ISSN: 1660-4601
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  • Beschreibung: Background: The aim of our study was to compare the number of lymph nodes removed during indocyanine green (ICG)-guided laparoscopic/robotic pelvic lymphadenectomy with standard systematic lymphadenectomy in endometrial cancer (EC) and cervical cancer (CC). Methods: This is a multicenter retrospective comparative study (Clinical Trial ID: NCT04246580; updated on 31 January 2023). Women affected by EC and CC who underwent laparoscopic/robotic systematic pelvic lymphadenectomy, with (cases) or without (controls) the use of ICG tracer injection within the uterine cervix, were included in the study. Results: The two groups were homogeneous for age (p = 0.08), Body Mass Index, International Federation of Gynaecology and Obstetrics (FIGO) stages (p = 0.41 for EC; p = 0.17 for CC), median estimated blood loss (p = 0.76), median operative time (p = 0.59), and perioperative complications (p = 0.66). Nevertheless, the number of lymph nodes retrieved during surgery was significantly higher (p = 0.005) in the ICG group (n = 18) compared with controls (n = 16). Conclusions: The accurate and precise dissection achieved with the use of the ICG-guided procedure was associated with a higher number of lymph nodes removed in the case of systematic pelvic lymphadenectomy for EC and CC.
  • Zugangsstatus: Freier Zugang