Sie können Bookmarks mittels Listen verwalten, loggen Sie sich dafür bitte in Ihr SLUB Benutzerkonto ein.
Medientyp:
E-Artikel
Titel:
Image-Guided Local Treatment for Unresectable Intrahepatic Cholangiocarcinoma—Role of Interventional Radiology
Beteiligte:
Fabritius, Matthias P.;
Ben Khaled, Najib;
Kunz, Wolfgang G.;
Ricke, Jens;
Seidensticker, Max
Erschienen:
MDPI AG, 2021
Erschienen in:
Journal of Clinical Medicine, 10 (2021) 23, Seite 5574
Sprache:
Englisch
DOI:
10.3390/jcm10235574
ISSN:
2077-0383
Entstehung:
Anmerkungen:
Beschreibung:
Intrahepatic cholangiocarcinoma is a highly aggressive malignancy with an increasing incidence in recent years. Prognosis is poor and most patients are not eligible for resection at the time of initial diagnosis due to the anatomic location, inadequate hepatic reserve, limiting comorbidities or metastatic disease. Several locoregional therapies from the field of interventional radiology exist for patients who are not amenable for surgery, or in case of local recurrence as a single treatment modality or combined with systemic treatment. To date, evidence is limited, with most conclusions drawn from single-center studies with small patient cohorts, often treated in the salvage situation or for local recurrence after initial resection. Nevertheless, the results are promising and suggest a survival benefit in selected patients. This narrative review focuses on the use of different locoregional treatment options for intrahepatic cholangiocarcinoma.