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Medientyp:
E-Artikel
Titel:
Atlantinone A, a Meroterpenoid Produced by Penicillium ribeum and Several Cheese Associated Penicillium Species
Beteiligte:
Dalsgaard, Petur W.;
Petersen, Bent O.;
Duus, Jens Ø.;
Zidorn, Christian;
Frisvad, Jens C.;
Christophersen, Carsten;
Larsen, Thomas O.
Erschienen:
MDPI AG, 2012
Erschienen in:
Metabolites, 2 (2012) 1, Seite 214-220
Sprache:
Englisch
DOI:
10.3390/metabo2010214
ISSN:
2218-1989
Entstehung:
Anmerkungen:
Beschreibung:
Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this study the compound was found to be produced at standard growth conditions by the following species; P. solitum, P. discolor, P. commune, P. caseifulvum, P. palitans, P. novae-zeelandiae and P. monticola. A biosynthetic pathway to atlantinone A starting from andrastin A is proposed.