• Medientyp: E-Artikel
  • Titel: Cloning of Multidrug-Resistant Genes from Vibrio cholerae Non-O1 NCTC4716
  • Beteiligte: Begum, Anowara; Kuroda, Teruo; Tsuchiya, Tomofusa
  • Erschienen: Bangladesh Journals Online (JOL), 1970
  • Erschienen in: Bangladesh Journal of Microbiology
  • Sprache: Nicht zu entscheiden
  • DOI: 10.3329/bjm.v23i2.879
  • ISSN: 2408-8374; 1011-9981
  • Schlagwörter: General Medicine
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p>Both clinical and environmental multidrug-resistant strains of Vibrio cholerae (O1 and non-O1) have been reported from different parts of the world. In this study, we have cloned twenty-five genes associated drug resistance in Vibrio cholerae non-O1 NCTC4716 using shotgun cloning method. All of the cloned genes were introduced and expressed in a drug hypersusceptible host Escherichia coli KAM32. We observed elevated minimum inhibitory concentration (MIC) of various antimicrobial agents such as fluoroquinolones, aminoglycosides, ethidium bromide and others in all transformants. Keywords: Vibrio cholerae, Drug resistance, Drug-resistant genes, Cloning, Minimum inhibitory concentration (MIC)DOI: http://dx.doi.org/10.3329/bjm.v23i2.879 Bangladesh J Microbiol, Volume 23, Number 2, December 2006, pp 137-139</jats:p>