Beschreibung:
<jats:p>Objectives. In the present study we wanted to evaluate the efficiency of Rifaximin-α on acute infectious diarrhea. Materials and methods. We revised the literature, as well as the studies which have been published within recent years. Discussions and conclusions. Rifaximin-α is an nonabsorbable antibiotic, bactericid, with a wide spectrum of action. It is recommended in acute diarrheic syndromes without invasive mechanism. Its properties (lack of intestinal absorbtion, minimal effect on colonic flora and no medication interactions) confer Rifaximin-α an excellent safety profile. Taking into account its wide spectrum of action and its high intestinal concentrations, it is considered an efficient and safe option in the treatment of acute infectious noninvasive diarrhea, as well as in the treatment and the prophilaxy of traveller´s diarrhea. Further more ample studies are needed to evaluate its efficiency in the treatment of recurrent infections with Clostridium difficile.</jats:p>