Beschreibung:
<jats:p>
In the dental office, disinfection and sterilization are a matter of utmost importance for both the physician, the medical staff and the patient. Twelve N-(2-bromo-phenyl)-2-hydroxy-benzamide and N-(4-bromo-phenyl)-2-hydroxy-benzamide derivatives were synthesized and tested for antimicrobial activity against 6 bacterial and 2 fungal strains using the Disk diffusion method for susceptibility testing. The obtained results indicated that the N-(2-bromo-phenyl)-2-hydroxy-benzamide derivatives were more active against the tested microbes, inhibition zones of 6-12 mm being obtained, although the most effective compound against S. pyogenes proved to be N-(4-bromo-phenyl)-2-hydroxy-benzamide (14 mm inhibition zone). The tested compounds presented no effect against S. aureus, S. flexneri, S. typhimurium and C. parapsilopsis at the tested concentration.
</jats:p>