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Medientyp:
E-Artikel
Titel:
Les coccidioses aviaires : importance et perspectives de recherche
Beteiligte:
Naciri, Muriel;
Brossier, Fabien
Erschienen:
PERSEE Program, 2009
Erschienen in:
Bulletin de l'Académie Vétérinaire de France, 162 (2009) 1, Seite 47-50
Sprache:
Französisch
DOI:
10.4267/2042/47975
ISSN:
0001-4192
Entstehung:
Anmerkungen:
Beschreibung:
Avian coccidial infections are associated with a heavy economic burden. They are caused by obligate intracellular parasites of the genus Eimeria. These parasites are host specific and invade epithelial cells of animal intestines, causing severe damages that can lead to the host’s death. Prophylaxis relies on the use of anticoccidial drugs and vaccination. However, the vaccines’ high costs and the emergence of anticoccidial drug resistance highlight the need to develop alternative control methods. A transgenic population of Eimeria has been developed recently, and this new tool will help study, for the first time, the molecular mechanisms involved in Eimeria infectious processes. Besides, this main advance in basic research could lead, in the longer time, to the development of new vaccine preparations. In this communication, we will also discuss the use of parasitic protease inhibitors as new putative anticoccidial drugs.