• Medientyp: E-Artikel
  • Titel: Patterns of Lymph Node Recurrence in Colorectal Cancer Liver Metastases after Surgery: A Retrospective Longitudinal Study
  • Beteiligte: Yong, Tuck Leong; Houli, Nezor; Starkey, Graham; Nikfarjam, Mehrdad; Jones, Robert; Fink, Michael; Muralidharan, V.; Perini, Marcos; Christophi, Chris
  • Erschienen: Canadian Center of Science and Education, 2017
  • Erschienen in: Cancer and Clinical Oncology
  • Sprache: Nicht zu entscheiden
  • DOI: 10.5539/cco.v6n2p35
  • ISSN: 1927-4866; 1927-4858
  • Schlagwörter: Management, Monitoring, Policy and Law ; Geography, Planning and Development
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  • Beschreibung: <jats:p>Background: Hepatic resection is the standard treatment for resectable colorectal cancer liver metastases. There is evidence that lymphatics play a role in disease recurrence post-surgery. The aim of this retrospective study is to assess patterns of lymph node recurrence after liver resection. Methods: Patients who had liver resection for colorectal cancer metastasis between 1 January 2010 and 31 December 2015 at 2 institutions in Melbourne, Australia were included. Data was collected from databases located at the 2 surgical centres.Results: Seventy-four patients were included in the study. Follow-up period was for a mean of 31.4 months. Lymph node recurrence was seen in 39.2% of patients during follow-up. Initial recurrence sites after hepatectomy was mainly in visceral-site only. Lymph node recurrences became more prominent during subsequent Recurrence Stages (RS) (RS1 – 22.4%, RS2 – 50.0%, RS3 – 50.0%, RS4 – 71.4%, RS5 – 66.7%, and RS6 – 0%). No predictive factor showed statistically significant relation to development of nodal recurrence. Conclusion: Lymph node recurrences after hepatic resection for liver metastases usually occur subsequent to a visceral-site only metastasis. There is no predictive factor as to which nodal group would be involved due to the complexity of liver lymphatic drainage.</jats:p>
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