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Medientyp:
E-Artikel
Titel:
Variable Decay of Memory and its Recovery in Cycloheximide-Treated Mice
Beteiligte:
Squire, Larry R.;
Barondes, Samuel H.
Erschienen:
National Academy of Sciences of the United States of America, 1972
Erschienen in:Proceedings of the National Academy of Sciences of the United States of America
Sprache:
Englisch
ISSN:
0027-8424
Entstehung:
Anmerkungen:
Beschreibung:
<p>Mice were trained in an automated visual-discrimination task. When injected with cycloheximide before training, mice showed: (a) some impairment of memory within minutes after the beginning of training, (b) gradual development of total amnesia in less than 3 hr or in more than 6 hr after training, depending on the extent of training, and (c) spontaneous recovery of memory within 3 days after training. The results are consistent with the operation of three processes of memory storage: (i) a short-term process that is independent of protein synthesis, (ii) a long-term process that is dependent on protein synthesis, and (iii) a slow-developing memory storage that becomes apparent during the days after training.</p>