Erschienen:
National Academy of Sciences of the United States of America, 1981
Erschienen in:Proceedings of the National Academy of Sciences of the United States of America
Sprache:
Englisch
ISSN:
0027-8424
Entstehung:
Anmerkungen:
Beschreibung:
<p>In autotrophically grown Chlorella cells, glucose induces a hexose transport system but, at the same time, the synthesis of two amino acid transport systems is also induced. Thus, the rates of uptake of glycine, L-alanine, L-proline, and L-serine, all of which compete with each other for entry into the cells, increase more than 100-fold when the algae are pretreated with glucose. The rates of L-arginine and L-lysine uptake increase by a factor of 25 to 50. The accumulation of proline and arginine within the cells amounts to 200- and 600-fold, respectively. Glucose does not cause the positive effect on amino acid uptake by serving as metabolic substrate because the nonmetabolizable 6-deoxyglucose also acts as inducer. Cycloheximide prevents the induction. The induced transport system for the four neutral amino acids has a turnover with a half-life of 7 hr, which corresponds closely to the half-life of the hexose transport system. The transport system for the basic amino acids, on the other hand, disappears with a half-life of 25 hr.</p>