• Medientyp: E-Artikel
  • Titel: Detection of α-Transducin in Retinal Rods but not Cones
  • Beteiligte: Grunwald, Gerald B.; Gierschik, Peter; Nirenberg, Marshall; Spiegel, Allen
  • Erschienen: The American Association for the Advancement of Science, 1986
  • Erschienen in: Science
  • Sprache: Englisch
  • ISSN: 0036-8075; 1095-9203
  • Schlagwörter: Reports
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <p> The distribution in chicken retina of the α subunit of transducin, the guanine nucleotide-binding protein that couples light-dependent activation of rhodopsin with activation of guanosine 3′,5′-monophosphate phosphodiesterase, was determined with the aid of a specific antiserum. α-Transducin was found in rod photoreceptor cells but was not detected in cones. These results show that rods and cones differ with respect to α-transducin content and suggest that the processes of phototransduction may differ correspondingly in rods and cones. </p>