• Medientyp: E-Artikel
  • Titel: Vertebrate-Type Intron-Rich Genes in the Marine Annelid Platynereis dumerilii
  • Beteiligte: Raible, Florian; Tessmar-Raible, Kristin; Osoegawa, Kazutoyo; Wincker, Patrick; Jubin, Claire; Balavoine, Guillaume; Ferrier, David; Benes, Vladimir; de Jong, Pieter; Weissenbach, Jean; Bork, Peer; Arendt, Detlev
  • Erschienen: American Association for the Advancement of Science, 2005
  • Erschienen in: Science, 310 (2005) 5752, Seite 1325-1326
  • Sprache: Englisch
  • ISSN: 0036-8075; 1095-9203
  • Schlagwörter: Reports
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  • Beschreibung: Previous genome comparisons have suggested that one important trend in vertebrate evolution has been a sharp rise in intron abundance. By using genomic data and expressed sequence tags from the marine annelid Platynereis dumerilii, we provide direct evidence that about two-thirds of human introns predate the bilaterian radiation but were lost from insect and nematode genomes to a large extent. A comparison of coding exon sequences confirms the ancestral nature of Platynereis and human genes. Thus, the urbilaterian ancestor had complex, intron-rich genes that have been retained in Platynereis and human.