> Details
Polke, Markus
[Author];
Kondoh, Yasuhiro
[Author];
Wijsenbeek, Marlies
[Author];
Cottin, Vincent
[Author];
Walsh, Simon L. F.
[Author];
Collard, Harold R.
[Author];
Chaudhuri, Nazia
[Author];
Avdeev, Sergey
[Author];
Behr, Jürgen
[Author];
Calligaro, Gregory
[Author];
Corte, Tamera J.
[Author];
Flaherty, Kevin
[Author];
Funke-Chambour, Manuela
[Author];
Kolb, Martin
[Author];
Krisam, Johannes
[Author];
Maher, Toby M.
[Author];
Molina-Molina, Maria
[Author];
Morais, Antonio
[Author];
Moor, Catharina C.
[Author];
Morisset, Julie
[Author];
Pereira, Carlos
[Author];
Quadrelli, Silvia
[Author];
Selman, Moises
[Author];
Tzouvelekis, Argyrios
[Author];
[...]
Management of acute exacerbation of idiopathic pulmonary fibrosis in specialised and non-specialised ILD centres around the world
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- Media type: E-Article
- Title: Management of acute exacerbation of idiopathic pulmonary fibrosis in specialised and non-specialised ILD centres around the world
- Contributor: Polke, Markus [Author]; Kondoh, Yasuhiro [Author]; Wijsenbeek, Marlies [Author]; Cottin, Vincent [Author]; Walsh, Simon L. F. [Author]; Collard, Harold R. [Author]; Chaudhuri, Nazia [Author]; Avdeev, Sergey [Author]; Behr, Jürgen [Author]; Calligaro, Gregory [Author]; Corte, Tamera J. [Author]; Flaherty, Kevin [Author]; Funke-Chambour, Manuela [Author]; Kolb, Martin [Author]; Krisam, Johannes [Author]; Maher, Toby M. [Author]; Molina-Molina, Maria [Author]; Morais, Antonio [Author]; Moor, Catharina C. [Author]; Morisset, Julie [Author]; Pereira, Carlos [Author]; Quadrelli, Silvia [Author]; Selman, Moises [Author]; Tzouvelekis, Argyrios [Author]; Valenzuela, Claudia [Author]; Vancheri, Carlo [Author]; Vicens-Zygmunt, Vanesa [Author]; Wälscher, Julia [Author]; Wuyts, Wim [Author]; Bendstrup, Elisabeth [Author]; Kreuter, Michael [Author]
-
Published:
27 September 2021
- Published in: Frontiers in medicine ; 8(2021) vom: 27. Sept., Artikel-ID 699644, Seite 1-10
- Language: English
- DOI: 10.3389/fmed.2021.699644
- Identifier:
- Origination:
- Footnote:
- Description: Background: Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is a severe complication associated with a high mortality. However, evidence and guidance on management is sparse. The aim of this international survey was to assess differences in prevention, diagnostic and treatment strategies for AE-IPF in specialised and non-specialised ILD centres worldwide.Material and Methods: Pulmonologists working in specialised and non-specialised ILD centres were invited to participate in a survey designed by an international expert panel. Responses were evaluated in respect to the physicians' institutions.Results: Three hundred and two (65%) of the respondents worked in a specialised ILD centre, 134 (29%) in a non-specialised pulmonology centre. Similarities were frequent with regards to diagnostic methods including radiology and screening for infection, treatment with corticosteroids, use of high-flow oxygen and non-invasive ventilation in critical ill patients and palliative strategies. However, differences were significant in terms of the use of KL-6 and pathogen testing in urine, treatments with cyclosporine and recombinant thrombomodulin, extracorporeal membrane oxygenation in critical ill patients as well as antacid medication and anaesthesia measures as preventive methods.Conclusion: Despite the absence of recommendations, approaches to the prevention, diagnosis and treatment of AE-IPF are comparable in specialised and non-specialised ILD centres, yet certain differences in the managements of AE-IPF exist. Clinical trials and guidelines are needed to improve patient care and prognosis in AE-IPF.
- Access State: Open Access