• Media type: E-Article
  • Title: Fluorescent SAM analogues for methyltransferase based DNA labeling
  • Contributor: Goyvaerts, Vince; Van Snick, Sven; D'Huys, Laurens; Vitale, Raffaele; Helmer Lauer, Milena; Wang, Su; Leen, Volker; Dehaen, Wim; Hofkens, Johan
  • Published: Royal Society of Chemistry (RSC), 2020
  • Published in: Chemical Communications, 56 (2020) 22, Seite 3317-3320
  • Language: English
  • DOI: 10.1039/c9cc08938a
  • ISSN: 1359-7345; 1364-548X
  • Origination:
  • Footnote:
  • Description: In this work, the preparation of new S-adenosyl-l-methionine (SAM) analogues for sequence specific DNA labeling is evaluated. Fluorescent cofactors were synthesized and their applicability in methyltransferase based optical mapping is demonstrated.