Erschienen:
Royal Society of Chemistry (RSC), 2020
Erschienen in:
Chemical Communications, 56 (2020) 22, Seite 3317-3320
Sprache:
Englisch
DOI:
10.1039/c9cc08938a
ISSN:
1359-7345;
1364-548X
Entstehung:
Anmerkungen:
Beschreibung:
<p>In this work, the preparation of new <italic>S</italic>-adenosyl-<sc>l</sc>-methionine (SAM) analogues for sequence specific DNA labeling is evaluated. Fluorescent cofactors were synthesized and their applicability in methyltransferase based optical mapping is demonstrated.</p>