• Media type: E-Article
  • Title: Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligand
  • Contributor: Höing, Alexander; Struth, Robin; Beuck, Christine; Rafieiolhosseini, Neda; Hoffmann, Daniel; Stauber, Roland H.; Bayer, Peter; Niemeyer, Jochen; Knauer, Shirley K.
  • imprint: Royal Society of Chemistry (RSC), 2022
  • Published in: RSC Advances
  • Language: English
  • DOI: 10.1039/d2ra06019a
  • ISSN: 2046-2069
  • Origination:
  • Footnote:
  • Description: <jats:p>“Targeting two for the price of one” – a selective bisphosphate ligand allows dual inhibition of threonine aspartase 1 by simultaneously addressing independent key functions – its protein–protein interaction-based activation and enzymatic function.</jats:p>
  • Access State: Open Access