• Medientyp: E-Artikel
  • Titel: Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligand
  • Beteiligte: Höing, Alexander; Struth, Robin; Beuck, Christine; Rafieiolhosseini, Neda; Hoffmann, Daniel; Stauber, Roland H.; Bayer, Peter; Niemeyer, Jochen; Knauer, Shirley K.
  • Erschienen: Royal Society of Chemistry (RSC), 2022
  • Erschienen in: RSC Advances
  • Sprache: Englisch
  • DOI: 10.1039/d2ra06019a
  • ISSN: 2046-2069
  • Schlagwörter: General Chemical Engineering ; General Chemistry
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  • Beschreibung: <jats:p>“Targeting two for the price of one” – a selective bisphosphate ligand allows dual inhibition of threonine aspartase 1 by simultaneously addressing independent key functions – its protein–protein interaction-based activation and enzymatic function.</jats:p>
  • Zugangsstatus: Freier Zugang