> Detailanzeige

Doenhardt, Maren; Hufnagel, Markus; Diffloth, Natalie; Hübner, Johannes; Mauer, René; Schneider, Dominik T.; Simon, Arne; Tenenbaum, Tobias; Trotter, Andreas; Armann, Jakob; Berner, Reinhard; Abuleed, Aischa; Achenbach, Michal; Adamiak-Brych, Grazyna; Aderhold, Martina; Akanbi, Sandra; Akmeinasi, Madaa; Albers, Norbert; Ammann-Schnell, Louisa; Anders, Kristin; Andree, Theresa; Anhalt, Judith; Apel, Nils; Arens, Stefan; [...]

Epidemiology of 7375 children and adolescents hospitalized with COVID-19 in Germany, reported via a prospective, nationwide surveillance study in 2020–2022

Literatur-
verwaltung

Zur
Merkliste

Lösche von
Merkliste

Per Whatsapp teilen

Schließen

Merkliste



Sie können Bookmarks mittels Listen verwalten, loggen Sie sich dafür bitte in Ihr SLUB Benutzerkonto ein.
  • Medientyp: E-Artikel
  • Titel: Epidemiology of 7375 children and adolescents hospitalized with COVID-19 in Germany, reported via a prospective, nationwide surveillance study in 2020–2022
  • Beteiligte: Doenhardt, Maren; Hufnagel, Markus; Diffloth, Natalie; Hübner, Johannes; Mauer, René; Schneider, Dominik T.; Simon, Arne; Tenenbaum, Tobias; Trotter, Andreas; Armann, Jakob; Berner, Reinhard; Abuleed, Aischa; Achenbach, Michal; Adamiak-Brych, Grazyna; Aderhold, Martina; Akanbi, Sandra; Akmeinasi, Madaa; Albers, Norbert; Ammann-Schnell, Louisa; Anders, Kristin; Andree, Theresa; Anhalt, Judith; Apel, Nils; Arens, Stefan; [...]
  • Erschienen: Springer Science and Business Media LLC, 2024
  • Erschienen in: Scientific Reports
  • Sprache: Englisch
  • DOI: 10.1038/s41598-023-49210-1
  • ISSN: 2045-2322
  • Schlagwörter: Multidisciplinary
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Abstract</jats:title><jats:p>By means of a nationwide, prospective, multicenter, observational cohort registry collecting data on 7375 patients with laboratory-confirmed SARS-CoV-2 admitted to children's hospitals in Germany, March 2020–November 2022, our study assessed the clinical features of children and adolescents hospitalized due to SARS-CoV-2, evaluated which of these patients might be at highest risk for severe COVID-19, and identified underlying risk factors. Outcomes tracked included: symptomatic infection, case fatality, sequelae at discharge and severe disease. Among reported cases, median age was one year, with 42% being infants. Half were admitted for reasons other than SARS-CoV-2. In 27%, preexisting comorbidities were present, most frequently obesity, neurological/neuromuscular disorders, premature birth, and respiratory, cardiovascular or gastrointestinal diseases. 3.0% of cases were admitted to ICU, but ICU admission rates varied as different SARS-CoV-2 variants gained prevalence. Main risk factors linked to ICU admission due to COVID-19 were: patient age (&gt; 12 and 1–4 years old), obesity, neurological/neuromuscular diseases, Trisomy 21 or other genetic syndromes, and coinfections at time of hospitalization. With Omicron, the group at highest risk shifted to 1–4-year-olds. For both health care providers and the general public, understanding risk factors for severe disease is critical to informing decisions about risk-reduction measures, including vaccination and masking guidelines.</jats:p>
  • Zugangsstatus: Freier Zugang