> Detailanzeige

Young, Matthew D.; Mitchell, Thomas J.; Vieira Braga, Felipe A.; Tran, Maxine G. B.; Stewart, Benjamin J.; Ferdinand, John R.; Collord, Grace; Botting, Rachel A.; Popescu, Dorin-Mirel; Loudon, Kevin W.; Vento-Tormo, Roser; Stephenson, Emily; Cagan, Alex; Farndon, Sarah J.; Del Castillo Velasco-Herrera, Martin; Guzzo, Charlotte; Richoz, Nathan; Mamanova, Lira; Aho, Tevita; Armitage, James N.; Riddick, Antony C. P.; Mushtaq, Imran; Farrell, Stephen; Rampling, Dyanne; [...]

Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors

Literatur-
verwaltung

Zur
Merkliste

Lösche von
Merkliste

Per Whatsapp teilen

Schließen

Merkliste



Sie können Bookmarks mittels Listen verwalten, loggen Sie sich dafür bitte in Ihr SLUB Benutzerkonto ein.
  • Medientyp: E-Artikel
  • Titel: Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors
  • Beteiligte: Young, Matthew D.; Mitchell, Thomas J.; Vieira Braga, Felipe A.; Tran, Maxine G. B.; Stewart, Benjamin J.; Ferdinand, John R.; Collord, Grace; Botting, Rachel A.; Popescu, Dorin-Mirel; Loudon, Kevin W.; Vento-Tormo, Roser; Stephenson, Emily; Cagan, Alex; Farndon, Sarah J.; Del Castillo Velasco-Herrera, Martin; Guzzo, Charlotte; Richoz, Nathan; Mamanova, Lira; Aho, Tevita; Armitage, James N.; Riddick, Antony C. P.; Mushtaq, Imran; Farrell, Stephen; Rampling, Dyanne; [...]
  • Erschienen: American Association for the Advancement of Science (AAAS), 2018
  • Erschienen in: Science
  • Sprache: Englisch
  • DOI: 10.1126/science.aat1699
  • ISSN: 0036-8075; 1095-9203
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Pediatric and adult kidney tumors differ</jats:title> <jats:p> Understanding tumor origins and the similarities and differences between organ-specific cancers is important for determining treatment options. Young <jats:italic>et al.</jats:italic> generated more than 72,000 single-cell transcriptomes from healthy and cancerous human kidneys. From these data, they determined that Wilms tumor, a pediatric kidney cancer, originates from aberrant fetal cells, whereas adult kidney cancers are likely derived from a specific subtype of proximal convoluted tubular cell. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6402" page="594" related-article-type="in-this-issue" vol="361" xlink:href="10.1126/science.aat1699">594</jats:related-article> </jats:p>